SOUTH CAROLINA: Click this link to see all slave labor sites in the state.
- Statehood: 1788; some counties were established before South Carolina became a state
- COUNTIES: Click one of the counties below to see all plantations/ workplaces in that county.
| County | Year Est. | Details |
| Abbeville | 1785 | from Ninety-Six District |
| Anderson | 1826 | from Pendleton District |
| Barnwell | 1798 | from Orangeburg District |
| Bartholomew | 1785 | from Charleston District |
| Beaufort | 1769 | |
| Berkeley | 1682 | |
| Charleston | 1769 | |
| Chester | 1785 | |
| Chesterfield | 1785 | from Cheraws District |
| Claremont | 1785 | from Camden District |
| Colleton | 1682 | from Charleston District |
| Craven | 1682 | |
| Darlington | 1785 | from Cheraws District |
| Edgefield | 1785 | from Ninety-Six District |
| Fairfeild | 1785 | from Camden District |
| Georgetown | 1769 | |
| Granville | 1684 | |
| Greenville | 1786 | from Washington District and lands of Native Americans |
| Hilton | 1785 | from Beaufort District |
| Horry | 1802 | from Georgetown District |
| Kershaw | 1791 | from Claremont, Lancaster, Fairfield and Richland Counties |
| Kingston | 1785 | from Georgetown District |
| Lancaster | 1785 | from Camden District |
| Laurens | 1785 | from Ninety-Six District |
| Lewisburg | 1785 | from Orangeburg District |
| Lexington | 1785 | from Orangeburg District |
| Liberty | 1785 | from Georgetown District |
| Lincoln | 1785 | from Beaufort District |
| Marion | 1798 | from Georgetown District |
| Marlboro | 1785 | from Cheraws District |
| Newberry | 1785 | from Ninety-Six District |
| Orange | 1785 | from Orangeburg District |
| Orangeburg | 1769 | |
| Pendleton | 1789 | from land of Native Americans |
| Pickens | 1825 | from Pendleton District |
| Richland | 1785 | from Camden District |
| Salem | 1791 | from Claremont and Clarendon Counties |
| Shrewsberry | 1785 | from Beaufort District |
| Spartanburg | 1785 | from Ninety-Six District |
| Sumter | 1798 | from Camden District |
| Union | 1785 | from Ninety-Six District |
| Washington | 1785 | from Charleston District |
| Williamsburg | 1802 | from Georgetown District |
| Winton | 1785 | from Orangeburg District |
| Winyah | 1785 | from Georgetown District |
| York | 1785 | from Camden District |
Sankofagen 